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Properties and catalytic mechanism of -glutamyltranspeptidase from NX-2

WANG Qian, YAO Zhong, XUN Zhijing, XU Xiaoying, XU Hong, WEI Ping

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 4,   Pages 456-461 doi: 10.1007/s11705-008-0075-3

Abstract: The affinity parameter of GGT to D-Gln (Km) was 5.08 mmol·L and the maximum reaction rate of transpeptidation() was determined as 0.034 mmol·min·L, while the affinity parameter of GGT to -D-Gln-L-Trp (’) was 2.267

Keywords： catalytic mechanism     mmol·min·L     D-glutamine     affinity parameter     important practical    

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High-affinity T cell receptors redirect cytokine-activated T cells (CAT) to kill cancer cells

Synat Kang, Yanyan Li, Yifeng Bao, Yi Li

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 69-82 doi: 10.1007/s11684-018-0677-1

Abstract: Herein, we demonstrate that NY-ESO-1157–165 HLA-A*02:01-specific high-affinity TCR (HAT)-transducedFurthermore, the high-affinity TCR-CATs delivered significantly better activation and cytotoxicity than

Keywords： cytokine-activated T cells     high-affinity T cell receptor     cancer immunotherapy     TCR-CAT    

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Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-

Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4,   Pages 433-444 doi: 10.1007/s11705-014-1454-6

Abstract: All inhibitors exhibit varied binding affinity to A , in which KLVFF has the highest binding affinity

Keywords： Alzheimer’s disease     amyloid β-protein     peptide inhibitors     protein-protein interaction     molecular dynamics simulation    

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LC/MS/MS and radioisotope method combined for recognizing the affinity between catalpol and OCT2 transporter

Zhiyu ZHANG, Changxiao LIU, Duanyun SI, Rong LU, Xiulin YI

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 4,   Pages 436-442 doi: 10.1007/s11705-012-1222-4

Abstract: radioisotope method was used for the quantification of catalpol, a traditional Chinese medicine, to study the affinityThe results show that catalpol has a good affinity with OCT2-transfected S2 cells.

Keywords： catalpol     LC/MS/MS     OCT2    

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PtHAK5, a candidate for mediating high-affinity K

Haili YANG, Weidan ZHANG, Weiwei CHAI, Wenying WANG, Li GAO, Jing ZHANG, Yongping WANG, Suo-Min WANG

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 1,   Pages 108-117 doi: 10.15302/J-FASE-2018200

Abstract: results showed PtHAK5 consisted of 784 amino acids and shared over 80% homology with the identified high-affinityIn conclusion, PtHAK5 is a candidate for mediating high-affinity K uptake under low K conditions.

Keywords： K+ uptake     PtHAK5     Puccinellia tenuiflora     yeast complementation    

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Clean Burning Process of Coal Which Converts Pollutants into Value-added Products

Zhu Xuefang

Strategic Study of CAE 1999, Volume 1, Issue 1,   Pages 53-57

Abstract: resultants into value-added products is to add a special admixture in coal and grind them together to form affinitygranules, which are sprayed into the boiler of the power plant for affinity calcination.

Keywords： turning resultants into value-added products     quick burning and quick cooling     solid desulfurization     affinitygranules     affinity calcination    

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Processing parameter optimization of fiber laser beam welding using an ensemble of metamodels and MOABC

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 4, doi: 10.1007/s11465-022-0703-5

Abstract: In fiber laser beam welding (LBW), the selection of optimal processing parameters is challenging and plays a key role in improving the bead geometry and welding quality. This study proposes a multi-objective optimization framework by combining an ensemble of metamodels (EMs) with the multi-objective artificial bee colony algorithm (MOABC) to identify the optimal welding parameters. An inverse proportional weighting method that considers the leave-one-out prediction error is presented to construct EM, which incorporates the competitive strengths of three metamodels. EM constructs the correlation between processing parameters (laser power, welding speed, and distance defocus) and bead geometries (bead width, depth of penetration, neck width, and neck depth) with average errors of 10.95%, 7.04%, 7.63%, and 8.62%, respectively. On the basis of EM, MOABC is employed to approximate the Pareto front, and verification experiments show that the relative errors are less than 14.67%. Furthermore, the main effect and the interaction effect of processing parameters on bead geometries are studied. Results demonstrate that the proposed EM-MOABC is effective in guiding actual fiber LBW applications.

Keywords： laser beam welding     parameter optimization     metamodel     multi-objective    

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Determination of effective stress parameter of unsaturated soils: A Gaussian process regression approach

Pijush Samui, Jagan J

Frontiers of Structural and Civil Engineering 2013, Volume 7, Issue 2,   Pages 133-136 doi: 10.1007/s11709-013-0202-1

Abstract: article examines the capability of Gaussian process regression (GPR) for prediction of effective stress parametervolumetric water content ( ), residual water content ( ), bubbling pressure ( ), suction ( ) and fitting parameterA sensitivity analysis has been done to determine the effect of each input parameter on .

Keywords： unsaturated soil     effective stress parameter     Gaussian process regression (GPR)     artificial neural network    

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1000 MW ultra-supercritical turbine steam parameter optimization

FENG Weizhong

Frontiers in Energy 2008, Volume 2, Issue 2,   Pages 187-193 doi: 10.1007/s11708-008-0030-5

Abstract: The 2 × 1000 MW ultra-supercritical steam turbine of Shanghai Waigaoqiao Phase III project, which uses grid frequency regulation and overload control through an overload valve, is manufactured by Shanghai Turbine Company using Siemens technology. Through optimization, the steam pressure is regarded as the criterion between constant pressure and sliding pressure operation. At high circulating water temperature, the turbine overload valve is kept closed when the unit load is lower than 1000 MW while at other circulating water temperatures the turbine can run in sliding pressure operation when the unit load is higher than 1000 MW and the pressure is lower than 27 MPa This increases the unit operation efficiency. The 3D bending technology in the critical piping helps to reduce the project investment and minimize the reheat system pressure drop which improves the unit operation efficiency and safety. By choosing lower circulating water design temperature and by setting the individual Boiler Feedwater Turbine condenser to reduce the exhaust steam flow and the heat load to the main condenser, the unit average back pressure and the terminal temperature difference are minimized. Therefore, the unit heat efficiency is increased.
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Structural parameter design method for a fast-steering mirror based on a closed-loop bandwidth

Guozhen CHEN, Pinkuan LIU, Han DING

Frontiers of Mechanical Engineering 2020, Volume 15, Issue 1,   Pages 55-65 doi: 10.1007/s11465-019-0545-y

Abstract: This study proposes a structural parameter design approach for an FSM system based on the quantitative

Keywords： fast-steering mirror     structural parameter     PI controller     bandwidth     notch filter    

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Energy efficient cutting parameter optimization

Xingzheng CHEN, Congbo LI, Ying TANG, Li LI, Hongcheng LI

Frontiers of Mechanical Engineering 2021, Volume 16, Issue 2,   Pages 221-248 doi: 10.1007/s11465-020-0627-x

Abstract: Over the past 10 years, many researchers have been engaged in energy efficient cutting parameter optimizationThis paper conducts a comprehensive literature review of current studies on energy efficient cutting parameterCurrent studies on energy efficient cutting parameter optimization by using experimental design methodCombined with the current status, future research directions of energy efficient cutting parameter optimization

Keywords： energy efficiency     cutting parameter     optimization     machining process    

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Hierarchical parameter estimation of DFIG and drive train system in a wind turbine generator

Xueping PAN, Ping JU, Feng WU, Yuqing JIN

Frontiers of Mechanical Engineering 2017, Volume 12, Issue 3,   Pages 367-376 doi: 10.1007/s11465-017-0429-y

Abstract:

A new hierarchical parameter estimation method for doubly fed induction generator (DFIG) and drive

Keywords： wind turbine generator     DFIG     drive train system     hierarchical parameter estimation method     trajectory sensitivity    

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Variational mode decomposition based modal parameter identification in civil engineering

Mingjie ZHANG, Fuyou XU

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 5,   Pages 1082-1094 doi: 10.1007/s11709-019-0537-3

Abstract: An out-put only modal parameter identification method based on variational mode decomposition (VMD) isconducted to demonstrate the efficiency and highlight the superiority of the proposed method in modal parameterThe proposed method is proved to be efficient and accurate in modal parameter identification for bothlinear and nonlinear civil structures, including structures with closely spaced modes, sudden modal parameter

Keywords： modal parameter identification     variational mode decomposition     civil structure     nonlinear system     closely    

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Shallow foundation response variability due to soil and model parameter uncertainty

Prishati RAYCHOWDHURY,Sumit JINDAL

Frontiers of Structural and Civil Engineering 2014, Volume 8, Issue 3,   Pages 237-251 doi: 10.1007/s11709-014-0242-1

Abstract: The present work intends to investigate the effect of soil and model parameter uncertainty on the response

Keywords： shallow foun dation     sensitivity analysis     centrifuge data     first-order-second-moment (FOSM) method     parameter    

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Parameter studies on impact in a lap joint

Amir M. RAHMANI,Elizabeth K. ERVIN

Frontiers of Mechanical Engineering 2015, Volume 10, Issue 1,   Pages 64-77 doi: 10.1007/s11465-014-0322-x

Abstract: Each parameter’s effect on system response is presented including unstable regions, unique trend

Keywords： impact mechanics     contact     joint behaviour     modal analysis     parameter study    

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Title Author Date Type Operation

Properties and catalytic mechanism of -glutamyltranspeptidase from NX-2

WANG Qian, YAO Zhong, XUN Zhijing, XU Xiaoying, XU Hong, WEI Ping

Journal Article

High-affinity T cell receptors redirect cytokine-activated T cells (CAT) to kill cancer cells

Synat Kang, Yanyan Li, Yifeng Bao, Yi Li

Journal Article

Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-

Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG

Journal Article

LC/MS/MS and radioisotope method combined for recognizing the affinity between catalpol and OCT2 transporter

Zhiyu ZHANG, Changxiao LIU, Duanyun SI, Rong LU, Xiulin YI

Journal Article

PtHAK5, a candidate for mediating high-affinity K

Haili YANG, Weidan ZHANG, Weiwei CHAI, Wenying WANG, Li GAO, Jing ZHANG, Yongping WANG, Suo-Min WANG

Journal Article

Clean Burning Process of Coal Which Converts Pollutants into Value-added Products

Zhu Xuefang

Journal Article

Processing parameter optimization of fiber laser beam welding using an ensemble of metamodels and MOABC

Journal Article

Determination of effective stress parameter of unsaturated soils: A Gaussian process regression approach

Pijush Samui, Jagan J

Journal Article

1000 MW ultra-supercritical turbine steam parameter optimization

FENG Weizhong

Journal Article

Structural parameter design method for a fast-steering mirror based on a closed-loop bandwidth

Guozhen CHEN, Pinkuan LIU, Han DING

Journal Article

Energy efficient cutting parameter optimization

Xingzheng CHEN, Congbo LI, Ying TANG, Li LI, Hongcheng LI

Journal Article

Hierarchical parameter estimation of DFIG and drive train system in a wind turbine generator

Xueping PAN, Ping JU, Feng WU, Yuqing JIN

Journal Article

Variational mode decomposition based modal parameter identification in civil engineering

Mingjie ZHANG, Fuyou XU

Journal Article

Shallow foundation response variability due to soil and model parameter uncertainty

Prishati RAYCHOWDHURY,Sumit JINDAL

Journal Article

Parameter studies on impact in a lap joint

Amir M. RAHMANI,Elizabeth K. ERVIN

Journal Article